Comparative effectiveness research, osteo-arthritis in knees.
platelet-rich plasma -vs- corticosteroid injection…….
“Evidence on the effect of platelet-rich plasma in treating osteoarthritis is insufficient. Therefore, the present study compares the effects of a one-time injection of platelet-rich plasma and corticosteroid”.
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“In the present randomized double blind clinical trial, the participants who suffered from knee osteoarthritis (Grades II/III), were randomly divided into two groups: intra articular injection of platelet-rich plasma and corticosteroid.”
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“….assessed before, 2-months, and 6-months after interventions.”
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“41 participants (48 knees) were involved in the research (66.7% women; average age of 61.1±7.0 years old). Compared to the group treated with corticosteroid, pain relief, symptom free, activities of daily living and quality of life in the platelet-rich plasma group were significantly higher….”
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“Platelet-rich plasma was significantly more helpful for relieving patients’ pain compared to corticosteroids.”
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“Our study demonstrated that one shot of platelet-rich plasma injection, decreased joint pain more and longer-term, alleviated the symptoms, and enhanced the activity of daily living and quality of life in short-term duration in comparison with corticosteroid.”
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B. Forogh, et al
Effect of single injection of platelet-rich plasma in comparison with corticosteroid on knee osteoarthritis: a double-blind randomized clinical trial
The Journal of Sports Medicine and Physical Fitness — Volume 56 #7&8 — July-August 2016 — page 901