chronic stress, adrenalin receptors, & cancer cell proliferation…..
“Chronic stress accelerates metastasis – the main cause of death in cancer patients – through the activation of β-adrenoceptors (βARs).”
“….to investigate the contribution of β2-adrenoceptor signaling in tumor cells to metastasis in vivo, we used RNA interference to generate MDA-MB-231HM breast cancer cells that are deficient in β2-adrenoceptors.”
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“These findings highlight a crucial role for β2-adrenoceptor tumor cell signaling in the adverse effects of stress on metastasis, and indicate that it may be necessary to block β2-adrenoceptors on tumor cells to fully control metastatic progression.”
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A.Chang, et al
β2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer
Brain, Behavior, and Immunity — Volume 57 — October 2016 — page 106
cognitive behavioral therapy -vs- tinnitus……
“Tinnitus has a substantially negative impact on quality of life in up to 5% of the general population. Internet-based cognitive-behavioral treatment has been shown to be effective in a few trials. The aim of our study was to investigate internet-based cognitive-behavioral treatment for tinnitus by using a randomized controlled trial.”
“Patients with severe tinnitus-related distress were randomly assigned to therapist-guided internet-based cognitive-behavioral treatment or to a moderated online discussion forum.”
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“Within-group effects for the internet-based cognitive-behavioral treatment, from pretreatment to follow-up, were substantial in regard to tinnitus-related distress….”
“Using a randomized controlled trial design, we replicated prior findings regarding positive effects of internet-based cognitive-behavioral treatment on tinnitus-related distress and associated symptoms. Implementing internet-based cognitive-behavioral treatment for tinnitus into regular health care will be an important next step to increase access to treatment for patients with tinnitus.”
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C. Weise-Kleinstäuber
Internet-Delivered Cognitive-Behavior Therapy for Tinnitus: A Randomized Controlled Trial
Psychosomatic Medicine — Volume 78 #4 — May 2016