Traditional approach to cancer treatment. Long term outcomes……

"Tamoxifen is most commonly prescribed for patients with hormone-sensitive breast cancer and exerts agonistic/antagonistic effects on estrogen receptors throughout the body. Accumulating evidence has revealed that breast cancer patients receiving Tamoxifen manifest cognitive dysfunction."
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"In the present study, we sought to explore the attention function of premenopausal women with hormone receptor-positive breast cancer treated with Tamoxifen using the attention network test."
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"Our results indicated that patients in the Tamoxifen group had significant deficits in their executive control component but not in the alerting or orienting components. Moreover, the patients showed poor executive function performance in the neuropsychological tests. Additionally, in the Tamoxifen group, significant correlations were found between the decreased efficiency of the executive control component and their reduced performance in executive function tests."
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"This study demonstrates that premenopausal women with hormone receptor-positive breast cancer treated with Tamoxifen have impairment of the executive attention network and that this impairment was associated with differences in executive function performance."

X.Chen, et al
Impairment of the executive attention network in premenopausal women with hormone receptor-positive breast cancer treated with tamoxifen
Psychoneuroendocrinology -- Volume 75 -- January 2017 

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"Cranial radiotherapy is a known risk factor for neurocognitive impairment in survivors of childhood acute lymphoblastic leukemia. Understanding the nature of cognitive dysfunction during adulthood in acute lymphoblastic leukemia survivors is important as it has an impact on major life situations."
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"38 acute lymphoblastic leukemia survivors were investigated 34 years after diagnosis."
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"Median-age was 38 (27–46) years."
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"Acute lymphoblastic leukemia survivors scored lower than controls in vocabulary, memory, learning capacity, spatial ability, executive functions and attention 34 years after acute lymphoblastic leukemia treatment."
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"Compared to controls acute lymphoblastic leukemia survivors had reduced white matter and grey matter volumes. ALL survivors had lower levels of white matter."
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"The present study shows impaired brain metabolism.....reduced brain volumes and neurocognitive impairment in childhood acute lymphoblastic leukemia survivors treated with cranial radiotherapy and chemotherapy, despite complete hormone substitution."
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"We also report an impairment of metabolites correlated to time since treatment and a progressive impairment in sustained attention, suggesting an accelerated aging in the irradiated brain."
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"Following these survivors many decades, or throughout life, after treatment with cranial radiotherapy and chemotherapy is highly warranted for a broader understanding of long-term outcome in this patient group."
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C.Follin, et al
Impaired brain metabolism and neurocognitive function in childhood leukemia survivors despite complete hormone supplementation in adulthood
Psychoneuroendocrinology -- Volume 73 -- November 2016 -- page 157
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TheETG cancer repair —– http://theetgtrackclub.com/documents/TheETGcancerkill.pdf