“The Patient Protection and Affordable Care Act of 2010 brought attention to adverse drug events in national patient safety efforts.”
“…..emergency department visits for adverse drug events in the United States in 2013-2014 and describe changes in emergency department visits for adverse drug events since 2005-2006.”
“…..data from 42,585 cases…..in 2013 and 2014 and 27.3% of emergency department visits for adverse drug events resulted in hospitalization.”
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“An estimated 34.5% emergency department visits for adverse drug events occurred among adults aged 65 years or older in 2013-2014 compared with an estimated 25.6% in 2005-2006; older adults experienced the highest hospitalization rates (43.6%).”
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“Anticoagulants, antibiotics, and diabetes agents were implicated in an estimated 46.9% emergency department visits for adverse drug events……”
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“Among children aged 5 years or younger, antibiotics were the most common drug class implicated. Among children and adolescents aged 6 to 19 years, antibiotics also were the most common drug class implicated (31.8%) in emergency department visits for adverse drug events, followed by antipsychotics (4.5%).”
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“Among older adults (aged ≥65 years), 3 drug classes (anticoagulants, diabetes agents, and opioid analgesics) were implicated in an estimated 59.9% emergency department visits for adverse drug events….”
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N. Shehab, et al
US Emergency Department Visits for Outpatient Adverse Drug Events, 2013-2014
Journal Of The American Medical Association — Volume 316 #20 — November 22/29, 2016 — page 2115

“……the benefits that US health care currently deliver may not outweigh the aggregate health harm it imparts.”
[Journal Of The American Medical Association…Volume 302 #1..July 1, 2009…page 89 – 91]