“Studies have shown an inverse association between the risk of breast cancer in women and physical activity. However, information on the association between cardiorespiratory fitness assessed objectively by a standardized test and the risk of developing breast cancer is limited.”
“To examine the cardiorespiratory fitness-breast cancer risk association in healthy females.”
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“This retrospective study was derived from the Exercise Testing and Health Outcomes Study cohort ( n = 750,302).”
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“Female participants ( n = 44,463; mean age ± SD; 55.1 ± 8.9 yr) who completed an exercise treadmill test evaluation at the Veterans Affairs Medical Centers nationwide from 1999 to 2020 were studied.”
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“During 438,613 person-years of observation, 994 women developed breast cancer.”
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“After controlling for covariates, the risk of breast cancer was inversely related to exercise capacity.”
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“When risk was assessed across cardiorespiratory fitness categories with the Least-fit group as the referent, the risk was 18% lower for Low-fit women…..31% for Moderate-fit….and 40% for Fit.”
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“We observed an inverse and graded association between cardiorespiratory fitness and breast cancer risk in women. Thus, encouraging women to improve cardiorespiratory fitness may help attenuate the risk of developing breast cancer.”
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J, Katsaroli, et al
The Association between Cardiorespiratory Fitness and the Risk of Breast Cancer in Women
Medicine & Science In Sports & Exercise — Volume 56 #6 — June 2024 — page 1134