“People with obesity have high circulating bile acids. Although aerobic fitness favors low circulating bile acids, the effect of training intensity before clinically meaningful weight loss on bile acids is unclear.”

“This study aimed to test the hypothesis that 2 weeks of interval versus continuous exercise would lower plasma bile acids in relation to insulin sensitivity.”

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Twenty-three older adults with prediabetes were randomized to 12 work-matched bouts of interval training at 3 minutes at 50% heart rate peak and 3 min at 90% heart rate peak or continuous training) at 70% heart rate peak cycling training for 60 minutes per day over 2 weeks.”

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“A 180-minutes 75-gram oral glucose tolerance test was performed to assess glucose tolerance, insulin sensitivity, and metabolic flexibility….”

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“Short-term training lowers some bile acids in relation to insulin sensitivity independent of intensity.”

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S.K.Malin, et al

Exercise Training Independent of Intensity Lowers Plasma Bile Acids in Prediabetes

Medicine & Science In Sports & Exercise — Volume 56 #6 — June 2024 — page 1009